Generation of a gene-corrected isogenic human iPSC line (CSUASOi006-A-1) from a retinitis pigmentosa patient with heterozygous c.5792C > T mutation in the PRPF8 gene_2024年_学术论文_科研成果_最新资讯

Generation of a gene-corrected isogenic human iPSC line (CSUASOi006-A-1) from a retinitis pigmentosa patient with heterozygous c.5792C > T mutation in the PRPF8 gene

发布日期： 2026-06-09

Xihao Sun , Yuqin Liang , Chunwen Duan , Xujie Liu , Yalan Zhou , Shengru Mao , Zekai Cui , Jianing Gu , Chengcheng Ding , Jiansu Chen , Shibo Tang

Retinal organoids with X-linked retinoschisis RS1 (E72K) mutation exhibit a photoreceptor developmental delay and are rescued by gene augmentation therapy

Generation of a gene-corrected isogenic human iPSC line (CSUASOi006-A-1) from a retinitis pigmentosa patient with heterozygous c.5792C > T mutation in the PRPF8 gene