2025年_爱尔眼科研究所

2025-10

24

The role of inflammation in myopic retinopathy

https://pubmed.ncbi.nlm.nih.gov/40909333/
2025-05

03

CRISPR/Cas9-mediated generation of a human induced pluripotent stem cell line with PRPF6 c.2699 G > A mutation to model retinitis pigmentosa

ABSTRACTPRPF6, located on chromosome 20, is required for the formation of the sp...
2025-05

02

Retinal organoids with X-linked retinoschisis RS1 (E72K) mutation exhibit a photoreceptor developmental delay and are rescued by gene augmentation therapy

AbstractBackground X-linked juvenile retinoschisis (XLRS) is an inherited disea...
2025-05

02

Risk Factors for Focal Choroidal Excavation Concurrent with Chorioretinal Disease: Evaluated by Spectral-Domain OCT

Purpose: To investigate the risk factors for patients with focal choroidal excav...
2025-05

02

Generation of a gene-corrected isogenic human iPSC line (CSUASOi006-A-1) from a retinitis pigmentosa patient with heterozygous c.5792C > T mutation in the PRPF8 gene

AbstractRetinitis pigmentosa (RP) is a common inherited retinal disease characte...
2025-05

02

Introduction of an RS1 mutation causative variant consistent with identified XLRS patient using CRISPR/Cas9 technology in normal iPSC

AbstractX-linked retinoschisis (XLRS) is a common retinal genetic disease that o...
2025-05

02

Novel full-thickness biomimetic corneal model for studying pathogenesis and treatment of diabetic keratopathy

AbstractDiabetic keratopathy (DK), a significant complication of diabetes, often...
2025-05

01

The complement pathway as a therapeutic target for neovascular age-related macular degenerationmediated subretinal fibrosis

AbstractNeovascular age-related macular degeneration (nAMD) is the leading cause...